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Comparative Efficacy Of Various Drugs Against Gastrodiscus In Horses

By: Wasim Ahmad Malik | Dr. Khalid Pervez, Prof.CMS.
Contributor(s): Dr.Muhammad Sarwar Khan | Mr. Kamran | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2003Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0795,T Dissertation note: This study was conducted to work out the prevalence of gastrodiscus infection in Lahore district and to check the efficacy of three different drugs i.e. Oxfendazole, Albendazole and Ivermectin againstastrodiscus infection in horses. This disease is cosmopolitan in distribution. Five hundred faecal samples of horses were collected and coprological examined by fresh smear method to determine 30 naturally infected horses by Qastrodiscus infection. These animals were divided into three groups i.e. group A, group B and group C. Each group was comprising of 10 animals. Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin, respectively. The prevalence of gastrodiscus infection at Lahore area o.nd out to be 6%. The eggs per gram (EPG) counts was estimated using MacMaster technique at zero day (pre-medication), 3rd day, 7th day and 14th day (post-medication). Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin at companies recommended dose rate of 1.2 ml/2 kg body weight, 1 ml/13 kg body weight and 1.0 ml/50 kg body weight, respectively. After medication at 3rd, 7th and 14th day EPG count was measured. It was observed that at 3rd day Oxfendazole, Albendazole and Ivermectin showed the efficacy 51.36%, 60.52% and 17.5%, respectively. At 7th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 58.18%, 72.63% and 7.5%, respectively. At 14th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 59.09%, 75.26% and 3.5%, respectively. The average efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 56.21%, 69.47% and 9.5%, respectively. Hence Oxfendazole and Abendazole showed better results as compared to Ivermectin. It was concluded Oxfendazole and Albendazole were safe against Gastrodiscus in horses.
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This study was conducted to work out the prevalence of gastrodiscus infection in Lahore district and to check the efficacy of three different drugs i.e. Oxfendazole, Albendazole and Ivermectin againstastrodiscus infection in horses. This disease is cosmopolitan in distribution.
Five hundred faecal samples of horses were collected and coprological examined by fresh smear method to determine 30 naturally infected horses by Qastrodiscus infection.
These animals were divided into three groups i.e. group A, group B and group C. Each group was comprising of 10 animals. Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin, respectively. The prevalence of gastrodiscus infection at Lahore area o.nd out to be 6%. The eggs per gram (EPG) counts was estimated using MacMaster technique at zero day (pre-medication), 3rd day, 7th day and 14th day (post-medication). Groups A, B and C were treated with Oxfendazole, Albendazole and Ivermectin at companies recommended dose rate of 1.2 ml/2 kg body weight, 1 ml/13 kg body weight and 1.0 ml/50 kg body weight, respectively.

After medication at 3rd, 7th and 14th day EPG count was measured. It was observed that at 3rd day Oxfendazole, Albendazole and Ivermectin showed the efficacy 51.36%, 60.52% and 17.5%, respectively.

At 7th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 58.18%, 72.63% and 7.5%, respectively.

At 14th day the efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 59.09%, 75.26% and 3.5%, respectively.

The average efficacy of Oxfendazole, Albendazole and Ivermectin was found to be 56.21%, 69.47% and 9.5%, respectively. Hence Oxfendazole and Abendazole showed better results as compared to Ivermectin. It was concluded Oxfendazole and Albendazole were safe against Gastrodiscus in horses.

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